I’m sure there are several times during the day that you are interrupted from the phone, people stopping by your office, instant messaging, and even your personal & work blackberry. So it's critical that you set aside uninterrupted time to process and organize your email.
Many email messages require you to make a decision. The best decisions require focus, and focus requires uninterrupted attention. Establish a regular time each day to process your email so that you can empty your Inbox. Of course, you can scan your email during the day for urgent messages or requests. Mark 2 or 3 times during the day that are dedicated to answering & going through your email. Maybe 10am & 4pm work for you. What ever times are good, make sure to stick with it & make it an appointment on your calendar. This way you won’t feel overwhelmed about your emails & can control your inbox clutter.
What to do about those other 3000+ emails currently in your inbox? I'm sure I will blog about this another day but until then . . . slowly start cleaning out your inbox by (1) taking care of every email that you get TODAY & then (2) commit to taking care of one ADDITIONAL day's email. Slow & steady wins the race so stop stressing about it ;-)